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See how Ozempic® compares to other medicines in head-to-head studies

Ozempic® lowers blood sugar and A1C

Ozempic® has been proven to significantly lower blood sugar and A1C.

Ozempic® vs Trulicity®
Ozempic® vs Bydureon®
Ozempic® vs Januvia®
Ozempic® vs Lantus®

Ozempic® lowered A1C better

A 40-week study compared Ozempic® 0.5 mg with Trulicity® 0.75 mg and Ozempic® 1 mg with Trulicity® 1.5 mg in 1201 adults with type 2 diabetes who were taking metformin.

Average change in A1C

Chart 2
Chart 3

The most common side effects of Ozempic® may include nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation.

In the same study, Ozempic® helped more people reach an A1C goal of less than 7%.

51%

of people with a starting A1C of 8.2% who took 0.75 mg Trulicity® lowered their A1C below 7%

VS

65%

of people with a starting A1C of 8.3% who took 0.5 mg Ozempic® lowered their A1C below 7%

63%

of people with a starting A1C of 8.2% who took 1.5 mg Trulicity® lowered their A1C below 7%

VS

73%

of people with a starting A1C of 8.2% who took 1 mg Ozempic® lowered their A1C below 7%

Ozempic® is not for weight loss

Ozempic® was shown to help people lose more weight than these type 2 diabetes medicines.

Ozempic® is not a weight-loss drug. It is a medicine for adults with type 2 diabetes that, along with diet and exercise, may improve blood sugar.

Ozempic® vs Trulicity®
Ozempic® vs Bydureon®
Ozempic® vs Januvia®
Ozempic® vs Lantus®

People lost more than double the weight on Ozempic® vs Trulicity®

Results are from a 40-week study that compared Ozempic® 0.5 mg with Trulicity® 0.75 mg and Ozempic® 1 mg with Trulicity® 1.5 mg in 1201 adults with type 2 diabetes who were taking metformin. While many people in clinical trials lost weight, some did gain weight. Ozempic® is not a weight-loss drug.

Average
starting weight

Weight loss comparison
Weight loss comparison

Selected Important Safety Information:

Ozempic® may cause serious side effects, including:

  • gallbladder problems. Gallbladder problems have happened in some people who take Ozempic®. Tell your healthcare provider right away if you get symptoms which may include: pain in your upper stomach (abdomen), fever, yellowing of the skin or eyes (jaundice) or clay-colored stools.

Are you struggling to lower your A1C goal with insulin alone?

In a randomized 30-week study of 397 adults with type 2 diabetes, Ozempic® was proven to help people with type 2 diabetes lower their A1C when added to a treatment plan that included taking insulin with or without metformin.

Chart 4

Ozempic® may cause serious side effects, including low blood sugar (hypoglycemia). Your risk of getting low blood sugar may be higher if you use Ozempic® with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include: dizziness or lightheadedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, and feeling jittery.

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